45 Minute Method | Unpacking the Research
The Basics
The combination of Coffee Berry Extract, American Ginseng, and Bacopa Monnieri may improve working memory and speed of attention within 45 minutes. A study showed that individuals on this supplement blend performed better in cognitive tasks compared to a placebo group. Additionally, an fNIRS scan revealed that the supplement improved blood flow to the brain, specifically showing less activation in the Prefrontal Cortex, which suggests a more efficient brain function with the active supplement. Despite these promising findings, research is ongoing and results have not yet been deemed conclusive by the EFSA, please form your own opinion of the scientific conclusions below.
45 Minute Method Research
Based on a single high-quality study, we, as responsible purveyors of herbal supplements, emphasize that while the findings are promising, research is ongoing and not yet deemed conclusive by the EFSA. Please form your own opinion on the scientific conclusions below.
Working Memory Improvement
The study found a significant enhancement in working memory performance on the N-back task post consumption of the herbal blend compared to placebo, reflected in terms of accuracy (p < .01) and response time (p < .05). This improvement is particularly notable in the 3-back task, indicating the supplement's efficacy in more demanding working memory tasks.
Quote: "Working memory task performance on the N-back task was significantly improved following active supplement consumption compared to placebo in terms of accuracy (p < .01) and response time (p < .05)."
Source: https://www.naturalhealthresearch.org/wp-content/uploads/2021/05/Combination-of-American-Ginseng-Whole-Coffee-Fruit-Extract-and-Bacopa-on-Working-Memory-and-Attention-in-Healthy-Adults.pdf
Increased Speed of Attention
Participants on the active supplement showed a notable improvement in the overall efficiency of task performance in the Stroop (congruent) response time, evidencing enhanced speed of attention post supplementation.
Quote: "The IES for the Stroop (congruent) response time showed there was a significant improvement (p < .05) in an overall efficiency of task performance for those in the active supplement condition compared to those in placebo."
Source: https://www.naturalhealthresearch.org/wp-content/uploads/2021/05/Combination-of-American-Ginseng-Whole-Coffee-Fruit-Extract-and-Bacopa-on-Working-Memory-and-Attention-in-Healthy-Adults.pdf
Enhanced Neural Efficiency
The fNIRS data revealed a decrease in activation in the left and right PFC during cognitively demanding tasks for the active supplement group, indicating increased neural efficiency.
Quote: "Improved performance was associated with a reduction of PFC activation (p < .001) related to effortful mental demand, reflecting increased neural efficiency concomitant with improved cognitive performance.”
Source: https://www.naturalhealthresearch.org/wp-content/uploads/2021/05/Combination-of-American-Ginseng-Whole-Coffee-Fruit-Extract-and-Bacopa-on-Working-Memory-and-Attention-in-Healthy-Adults.pdf
Improved Blood Flow to the Brain
The fNIRS change score manifested significant differences in the left and right PFC activation, which is associated with enhanced blood flow to these critical areas of the brain, fostering better cognitive performance.
Quote: "Significant differences in fNIRS change score were observed in left and right PFC, with the 3-back task resulting in less activation for the active supplement condition compared to placebo in both the right (p < .001) and left (p < .01) hemispheres."
Source: https://www.naturalhealthresearch.org/wp-content/uploads/2021/05/Combination-of-American-Ginseng-Whole-Coffee-Fruit-Extract-and-Bacopa-on-Working-Memory-and-Attention-in-Healthy-Adults.pdf
Ingredients
American Ginseng
American Ginseng Research
Improved Cognitive Function
This study provides the first evidence that acute administration of American ginseng (Panax quinquefolius) in healthy young adults can improve cognitive performance and increase calmness.
Source: Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952762/
Reduced Fatigue
Ginseng supplements may reduce fatigue and enhance physical performance, especially in people with cancer-related fatigue and chronic fatigue syndrome. However, more high-quality studies are needed to confirm these findings.
Source: Efficacy of Ginseng Supplements on Fatigue and Physical Performance: a Meta-analysis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102849/
Improved Blood Sugar Control
The results of this meta-analysis suggest that Panax ginseng supplements may be effective in improving blood sugar control in patients with type 2 diabetes. However, more well-designed and large-scale clinical trials are needed to confirm these findings and to determine the optimal dosage and duration of treatment.
Source: Efficacy of Panax ginseng supplements for improving blood sugar control in type 2 diabetes: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227417/
Reduced Stress and Anxiety
Ginseng has been shown to have beneficial effects on stress-related depression, anxiety, and the hypothalamic-pituitary-adrenal (HPA) axis. These effects are thought to be mediated by a variety of mechanisms, including modulation of the neuroendocrine system, the immune system, and the central nervous system. Ginseng may be a useful adjunctive therapy for patients with stress-related disorders.
Source: Effects of ginseng on stress-related depression, anxiety, and the hypothalamic–pituitary–adrenal axis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628357/
Enhanced Immune Function
American ginseng (Panax quinquefolius L.) has been shown to have a variety of immune-modulatory effects. It can enhance the activity of natural killer cells and macrophages, and it can also increase the production of antibodies and cytokines. American ginseng has also been shown to protect against a variety of infections, including the common cold, influenza, and herpes simplex virus. Overall, the evidence suggests that American ginseng can boost the immune system and help to protect against disease.
Source: Immune-modulatory effects of American ginseng (Panax quinquefolius L.): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757584/
What Makes Our American Ginseng Superior?
At Andïnn Organics, we believe in the power of nature and its ability to enhance our well-being. Here are the reasons why our American Ginseng stands out:
Organic and Pure
Our American Ginseng is 100% organic and pure. We ensure that no additives or unnecessary ingredients are added during the process. This means you are getting 100% American Ginseng in every serving, which is imperative for those who value unadulterated, high-quality supplements.
High Ginsenosides Content
Our American Ginseng boasts an impressive 80% ginsenosides. Ginsenosides are compounds believed to contribute largely to the Ginseng's properties. This high content is a testament to the potency and high-quality of our product.
Powerful Extract Ratio 40:1
Our American Ginseng has an extract ratio of 40:1. This means that for every gram of our extract powder, 40 grams of fresh American Ginseng roots have been used. This high ratio ensures that we capture the very essence of the Ginseng, providing you with a concentrated form of this powerful root.
In Conclusion
Our American Ginseng is superior because we believe in delivering only the best to our customers. From the organic and pure nature of our product to the high concentration of ginsenosides and a powerful extract ratio, each aspect of our American Ginseng is designed to offer you a potent supplement. We stand by the quality and potency of our American Ginseng, always aiming to provide you with the very best that nature has to offer.
Coming Soon
Bacopa Monnieri
Bacopa Monnieri Research
Cognition
Study 1: Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial (2016)
Conclusion: Bacopa monnieri significantly improved speed of visual information processing, learning rate, memory consolidation, and decreased anxiety with maximal effects after 12 weeks of administration.
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075615/
Study 2: Effects of Bacopa monnieri on Human Psychological Function: A Double-Blind, Placeb-Controlled Study (2013)
Conclusion: Bacopa monnieri significantly improved cognitive function, including attention, memory, and processing speed. It also reduced anxiety and improved mood.
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746283/
Memory
Study 1: Effects of a Standardized Bacopa monnieri Extract on Cognitive Performance, Anxiety, and Depression in the Elderly (2008)
Conclusion: Bacopa monnieri extract significantly improved cognitive performance in elderly adults, as well as reducing anxiety and depression.
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153866/
Study 2: Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease (2019)
Conclusion: Besides cognitive improvement, B monnieri can also enhance learning capability. Consumption of B monnieri for 3 months in 76 human subjects between 40 and 65 years of age in University of Wollongong, Australia resulted in significant effects on retention of new information.
Source: https://journals.sagepub.com/doi/full/10.1177/1177392819866412
Mood
Study 1: Effects of a Standardized Bacopa monnieri Extract on Cognitive Performance, Anxiety, and Depression in the Elderly (2008)
Conclusion: Bacopa monnieri extract significantly improved cognitive performance in elderly adults, as well as reducing anxiety and depression.
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153866/
What Makes Our Bacopa Monnieri Superior?
Organic Certification
At Andïnn Organics, we take pride in the quality and purity of our supplements. Our Bacopa Monnieri is both USDA and EU certified Organic. This certification is more than just a label, it's our commitment to you that we are providing a product that is free from harmful fertilizers and pesticides. When you choose our Bacopa, you are choosing a product that is as close to nature as possible.
Potent Extract Strength
Our Bacopa Monnieri stands out in its potency. With an extract strength of 30:1, it means that it takes 30 grams of fresh Bacopa Monnieri to produce just 1 gram of our extract. This high concentration ensures that you're getting the maximum benefit from each serving.
High Levels of Functional Compounds
We ensure that our Bacopa Monnieri is rich in its active compounds. With a whopping 50% bacosides, the active compounds that make Bacopa Monnieri beneficial, our supplement is one of the most potent on the market. This high level of functional compounds means that you are getting a superior product that delivers the benefits you expect from a Bacopa Monnieri supplement.
Pure and Clean
At Andïnn Organics, we believe in transparency and simplicity. Our Bacopa Monnieri is 100% pure with no additional fillers or additives. We believe that the best supplements are those that stay true to their natural origins, and that's why we ensure that our Bacopa Monnieri remains as unadulterated as possible.
Coffee Fruit
Coffee Fruit Research
Cognitive Benefits
Study 1: "Neurophysiological Effects of Whole Coffee Cherry [or Coffee Fruit / Berry] Extract in Older Adults with Subjective Cognitive Impairment (2021): A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Pilot Study"
Conclusion: "This pilot study provides preliminary evidence that WCCE may have beneficial effects on neurophysiological measures of cognitive function in older adults with SCI. However, larger and longer-term studies are needed to confirm these findings and to elucidate the underlying mechanisms of action."
Source: https://pubmed.ncbi.nlm.nih.gov/33498314/
Study 2: "Acute Low and Moderate Doses of a Caffeine-Free Polyphenol-Rich Coffeeberry Extract Improve Feelings of Alertness and Fatigue Resulting from the Performance of Fatiguing Cognitive Tasks (2018)"
Conclusion: "These findings suggest that a single dose of a caffeine-free polyphenol-rich coffeeberry extract can improve subjective feelings of alertness and fatigue resulting from the performance of fatiguing cognitive tasks. Further research is needed to confirm these findings and to investigate the underlying mechanisms of action."
Source: https://link.springer.com/article/10.1007/s41465-018-0118-8
Study 3: "Modulatory effect of coffee fruit extract on plasma levels of brain-derived neurotrophic factor in healthy subjects (2013)"
Abstract: The study examined Coffee Fruit Extract (CFE) impact on Brain-Derived Neurotrophic Factor (BDNF), vital for neurogenesis and synaptic plasticity, in 20 individuals. Post a single 500mg CFE dose, a significant rise in BDNF plasma levels was observed, hinting at CFE's potential to improve cognitive function. Further research is needed for confirmation and understanding long-term effects.
Source: https://www.researchgate.net/publication/234121243_Modulatory_effect_of_coffee_fruit_extract_on_plasma_levels_of_brain-derived_neurotrophic_factor_in_healthy_subjects
What Makes Our Coffee Fruit Superior?
Certified Organic
Our Coffee Fruit extract is USDA and EU certified organic. This prestigious certification means that our coffee berries are grown without the use of synthetic pesticides or fertilisers, ensuring you receive a product that's as clean and natural as possible. We’re committed to providing you with a product that is not only beneficial for your health, but also kind to the environment.
Impressive Extract Ratio
One of the key things that set our Coffee Fruit extract apart is its impressive extract ratio of 10:1. This means that it takes 10 grams of fresh coffee fruit to produce just 1 gram of our extract. This high concentration ensures that you’re getting the maximum amount of beneficial compounds in every serving.
Chlorogenic Acids Content
Our Coffee Fruit extract boasts a 10% Chlorogenic Acid content. Chlorogenic Acids are a family of substances that have been studied for their potential effects on health. While we make no specific health claims, we believe that the presence of these compounds adds to the overall quality of our Coffee Fruit extract.
Eco-Friendly Packaging
Finally, we believe that superior products deserve superior packaging. That's why our Coffee Fruit extract is packaged in eco-friendly materials. We prioritise the use of glass, paper, and metal materials over plastic wherever possible. This commitment to sustainability means that when you choose our Coffee Fruit extract, you’re not just making a choice that's good for you - it's good for the planet too.